High Nucleosome Occupancy Is Encoded at Human Regulatory Sequences

Active eukaryotic regulatory sites are characterized by open chromatin, and yeast promoters and transcription factor binding sites (TFBSs) typically have low intrinsic nucleosome occupancy. Here, we show that in contrast to yeast, DNA at human promoters, enhancers, and TFBSs generally encodes high i...

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Hlavní autoři: Tillo, Desiree, Kaplan, Noam, Moore, Irene K., Fondufe-Mittendorf, Yvonne, Gossett, Andrea J., Field, Yair, Lieb, Jason D., Widom, Jonathan, Segal, Eran, Hughes, Timothy R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817738/
https://ncbi.nlm.nih.gov/pubmed/20161746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009129
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