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Improved methods for magnetic purification of malaria parasites and haemozoin

BACKGROUND: Malaria parasites generate free haem upon catabolism of host haemoglobin during their intraerythrocytic growth cycle. In order to minimize oxidative toxicity of the ferric iron, the free haem molecules are polymerized into the biomineral beta-haematin (commonly referred to as haemozoin)....

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Autors principals: Kim, Charles C, Wilson, Emily B, DeRisi, Joseph L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817699/
https://ncbi.nlm.nih.gov/pubmed/20074366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-9-17
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