Contamination with E1A-Positive Wild-Type Adenovirus Accounts for Species-Specific Stimulation of Islet Cell Proliferation by CCK: A Cautionary Note

We have previously reported that adenovirus-mediated expression of preprocholecystokin (CCK) stimulates human and mouse islet cell proliferation. In follow-up studies, we became concerned that the CCK adenovirus might have been contaminated with a wild-type E1A-containing adenovirus. Here we show co...

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Autors principals: Lavine, Jeremy A., Raess, Philipp W., Davis, Dawn B., Rabaglia, Mary E., Presley, Brent K., Keller, Mark P., Beinfeld, Margery C., Kopin, Alan S., Newgard, Christopher B., Attie, Alan D.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817600/
https://ncbi.nlm.nih.gov/pubmed/20081104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0384
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