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A single-molecule assay for telomerase structure-function analysis

The activity of the telomerase ribonucleoprotein enzyme is essential for the maintenance of genome stability and normal cell development. Despite the biomedical importance of telomerase activity, detailed structural models for the enzyme remain to be established. Here we report a single-molecule ass...

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Detalhes bibliográficos
Main Authors: Wu, John Y., Stone, Michael D., Zhuang, Xiaowei
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817460/
https://ncbi.nlm.nih.gov/pubmed/19920121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1033
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