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Nonlinear Dynamics of Nonsynonymous (d(N)) and Synonymous (d(S)) Substitution Rates Affects Inference of Selection

Selection modulates gene sequence evolution in different ways by constraining potential changes of amino acid sequences (purifying selection) or by favoring new and adaptive genetic variants (positive selection). The number of nonsynonymous differences in a pair of protein-coding sequences can be us...

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Detalhes bibliográficos
Main Authors: Wolf, Jochen B. W., Künstner, Axel, Nam, Kiwoong, Jakobsson, Mattias, Ellegren, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817425/
https://ncbi.nlm.nih.gov/pubmed/20333200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evp030
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