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Properties of the ribosomal P2 protein autoantigen are similar to those of foreign protein antigens.

Approximately 15% of patients with systemic lupus erythematosus have autoantibodies that bind to a shared epitope previously shown to be located on the carboxyl-terminal 22 amino acids of three 60S ribosomal proteins, P0, P1, and P2 ("P proteins"). A hydrophilicity plot and fine epitope ma...

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Dettagli Bibliografici
Autori principali: Elkon, K, Bonfa, E, Llovet, R, Danho, W, Weissbach, H, Brot, N
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1988
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC281713/
https://ncbi.nlm.nih.gov/pubmed/2455896
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