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Properties of the ribosomal P2 protein autoantigen are similar to those of foreign protein antigens.
Approximately 15% of patients with systemic lupus erythematosus have autoantibodies that bind to a shared epitope previously shown to be located on the carboxyl-terminal 22 amino acids of three 60S ribosomal proteins, P0, P1, and P2 ("P proteins"). A hydrophilicity plot and fine epitope ma...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1988
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281713/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2455896/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.14.5186 |
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