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Clinical features and prognostic implications of TCF3-PBX1 and ETV6-RUNX1 in adult acute lymphoblastic leukemia

BACKGROUND: The t(9;22) and t(4;11) chromosomal translocations, which generate the BCR-ABL and MLL-AF4 fusion genes, define high-risk subtypes of acute lymphoblastic leukemia in adults. However, the prognostic impact of other rarer fusion genes is less well established in adult acute lymphoblastic l...

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Detalhes bibliográficos
Main Authors: Burmeister, Thomas, Gökbuget, Nicola, Schwartz, Stefan, Fischer, Lars, Hubert, Daniela, Sindram, Annette, Hoelzer, Dieter, Thiel, Eckhard
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817026/
https://ncbi.nlm.nih.gov/pubmed/19713226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.011346
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