A divalent switch drives H-NS/DNA-binding conformations between stiffening and bridging modes

Heat-stable nucleoid structuring protein (H-NS) is an abundant prokaryotic protein that plays important roles in organizing chromosomal DNA and gene silencing. Two controversial binding modes were identified. H-NS binding stimulating DNA bridging has become the accepted mechanism, whereas H-NS bindi...

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Bibliografiske detaljer
Main Authors: Liu, Yingjie, Chen, Hu, Kenney, Linda J., Yan, Jie
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2010
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816733/
https://ncbi.nlm.nih.gov/pubmed/20159954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1883510
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