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A divalent switch drives H-NS/DNA-binding conformations between stiffening and bridging modes
Heat-stable nucleoid structuring protein (H-NS) is an abundant prokaryotic protein that plays important roles in organizing chromosomal DNA and gene silencing. Two controversial binding modes were identified. H-NS binding stimulating DNA bridging has become the accepted mechanism, whereas H-NS bindi...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Cold Spring Harbor Laboratory Press
2010
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2816733/ https://ncbi.nlm.nih.gov/pubmed/20159954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1883510 |
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