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Characterization of a Chinese Hamster Ovary Cell Mutant Having a Mutation in Elongation Factor-2

Retroviral insertional mutagenesis provides an effective forward genetic method for identifying genes involved in essential cellular pathways. A Chinese hamster ovary cell line mutant resistant to several bacterial ADP-ribosylating was obtained by this approach. The toxins used catalyze ADP-ribosyla...

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Bibliografiske detaljer
Main Authors: Gupta, Pradeep K., Liu, Shihui, Leppla, Stephen H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816718/
https://ncbi.nlm.nih.gov/pubmed/20140093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009078
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