A Humanized Anti-VEGF Rabbit Monoclonal Antibody Inhibits Angiogenesis and Blocks Tumor Growth in Xenograft Models

Rabbit antibodies have been widely used in research and diagnostics due to their high antigen specificity and affinity. Though these properties are also highly desirable for therapeutic applications, rabbit antibodies have remained untapped for human disease therapy. To evaluate the therapeutic pote...

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Autors principals: Yu, Yanlan, Lee, Pierre, Ke, Yaohuang, Zhang, Yongke, Yu, Qiu, Lee, Jonathan, Li, Mingzhen, Song, Jialiang, Chen, Jungang, Dai, Jihong, Couto, Fernando Jose Rebelo Do, An, Zhiqiang, Zhu, Weimin, Yu, Guo-Liang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816707/
https://ncbi.nlm.nih.gov/pubmed/20140208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009072
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