Transient Dimers of Allergens

BACKGROUND: Allergen-mediated cross-linking of IgE antibodies bound to the FcεRI receptors on the mast cell surface is the key feature of the type I allergy. If an allergen is a homodimer, its allergenicity is enhanced because it would only need one type of antibody, instead of two, for cross-linkin...

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Autors principals: Rouvinen, Juha, Jänis, Janne, Laukkanen, Marja-Leena, Jylhä, Sirpa, Niemi, Merja, Päivinen, Tero, Mäkinen-Kiljunen, Soili, Haahtela, Tari, Söderlund, Hans, Takkinen, Kristiina
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816702/
https://ncbi.nlm.nih.gov/pubmed/20140203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009037
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