Reverse Genetics in Candida albicans Predicts ARF Cycling Is Essential for Drug Resistance and Virulence

Candida albicans, the major fungal pathogen of humans, causes life-threatening infections in immunocompromised individuals. Due to limited available therapy options, this can frequently lead to therapy failure and emergence of drug resistance. To improve current treatment strategies, we have combine...

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Main Authors: Epp, Elias, Vanier, Ghyslaine, Harcus, Doreen, Lee, Anna Y., Jansen, Gregor, Hallett, Michael, Sheppard, Don C., Thomas, David Y., Munro, Carol A., Mullick, Alaka, Whiteway, Malcolm
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816695/
https://ncbi.nlm.nih.gov/pubmed/20140196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000753
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