Reverse Genetics in Candida albicans Predicts ARF Cycling Is Essential for Drug Resistance and Virulence

Candida albicans, the major fungal pathogen of humans, causes life-threatening infections in immunocompromised individuals. Due to limited available therapy options, this can frequently lead to therapy failure and emergence of drug resistance. To improve current treatment strategies, we have combine...

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Detalhes bibliográficos
Main Authors: Epp, Elias, Vanier, Ghyslaine, Harcus, Doreen, Lee, Anna Y., Jansen, Gregor, Hallett, Michael, Sheppard, Don C., Thomas, David Y., Munro, Carol A., Mullick, Alaka, Whiteway, Malcolm
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816695/
https://ncbi.nlm.nih.gov/pubmed/20140196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000753
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