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Reverse Genetics in Candida albicans Predicts ARF Cycling Is Essential for Drug Resistance and Virulence

Candida albicans, the major fungal pathogen of humans, causes life-threatening infections in immunocompromised individuals. Due to limited available therapy options, this can frequently lead to therapy failure and emergence of drug resistance. To improve current treatment strategies, we have combine...

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Bibliografiske detaljer
Main Authors: Epp, Elias, Vanier, Ghyslaine, Harcus, Doreen, Lee, Anna Y., Jansen, Gregor, Hallett, Michael, Sheppard, Don C., Thomas, David Y., Munro, Carol A., Mullick, Alaka, Whiteway, Malcolm
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816695/
https://ncbi.nlm.nih.gov/pubmed/20140196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000753
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