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Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans
Epigenetic silencing of a fraction of ribosomal DNA (rDNA) requires association of the nucleolar chromatin-remodelling complex NoRC to 150–250 nucleotide RNAs (pRNA) that originate from an RNA polymerase I promoter located in the intergenic spacer separating rDNA repeats. Here, we show that NoRC-ass...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2816622/ https://ncbi.nlm.nih.gov/pubmed/20010804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.254 |
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