Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer

Hereditary diffuse gastric cancer (HDGC) is an autosomal dominant cancer susceptibility syndrome characterized by early-onset diffuse gastric cancer (DGC) and lobular breast cancer. E-cadherin (CDH1) heterozygous germline mutations and deletions are found in 40% of families. Independent of CDH1 alte...

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Autors principals: Pinheiro, Hugo, Bordeira-Carriço, Renata, Seixas, Susana, Carvalho, Joana, Senz, Janine, Oliveira, Patrícia, Inácio, Patrícia, Gusmão, Leonor, Rocha, Jorge, Huntsman, David, Seruca, Raquel, Oliveira, Carla
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Association Studies Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816607/
https://ncbi.nlm.nih.gov/pubmed/19965908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp537
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