A murine model of autosomal dominant neurohypophyseal diabetes insipidus reveals progressive loss of vasopressin-producing neurons

Familial neurohypophyseal diabetes insipidus (FNDI) is an autosomal dominant disorder caused by mutations in the arginine vasopressin (AVP) precursor. The pathogenesis of FNDI is proposed to involve mutant protein–induced loss of AVP-producing neurons. We established murine knock-in models of two di...

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Detalhes bibliográficos
Main Authors: Russell, Theron A., Ito, Masafumi, Ito, Mika, Yu, Richard N., Martinson, Fred A., Weiss, Jeffrey, Jameson, J. Larry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC281642/
https://ncbi.nlm.nih.gov/pubmed/14660745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318616
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