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Recipient-type specific CD4(+)CD25(+) regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia

CD4(+)CD25(+) regulatory T cells (Treg’s) play a pivotal role in preventing organ-specific autoimmune diseases and in inducing tolerance to allogeneic organ transplants. We and others recently demonstrated that high numbers of Treg’s can also modulate graft-versus-host disease (GVHD) if administered...

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Detalhes bibliográficos
Main Authors: Trenado, Aurélie, Charlotte, Frédéric, Fisson, Sylvain, Yagello, Micael, Klatzmann, David, Salomon, Benoît L., Cohen, José L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC281639/
https://ncbi.nlm.nih.gov/pubmed/14660744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317702
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