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Recipient-type specific CD4(+)CD25(+) regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
CD4(+)CD25(+) regulatory T cells (Treg’s) play a pivotal role in preventing organ-specific autoimmune diseases and in inducing tolerance to allogeneic organ transplants. We and others recently demonstrated that high numbers of Treg’s can also modulate graft-versus-host disease (GVHD) if administered...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC281639/ https://ncbi.nlm.nih.gov/pubmed/14660744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317702 |
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