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Reduced myofibrillar connectivity and increased Z-disk width in nebulin-deficient skeletal muscle

A prominent feature of striated muscle is the regular lateral alignment of adjacent sarcomeres. An important intermyofibrillar linking protein is the intermediate filament protein desmin, and based on biochemical and structural studies in primary cultures of myocytes it has been proposed that desmin...

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Detalhes bibliográficos
Main Authors: Tonino, Paola, Pappas, Christopher T., Hudson, Bryan D., Labeit, Siegfried, Gregorio, Carol C., Granzier, Henk
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816184/
https://ncbi.nlm.nih.gov/pubmed/20053633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.042234
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