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The Effect of Orthology and Coregulation on Detecting Regulatory Motifs

BACKGROUND: Computational de novo discovery of transcription factor binding sites is still a challenging problem. The growing number of sequenced genomes allows integrating orthology evidence with coregulation information when searching for motifs. Moreover, the more advanced motif detection algorit...

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Autori principali: Storms, Valerie, Claeys, Marleen, Sanchez, Aminael, De Moor, Bart, Verstuyf, Annemieke, Marchal, Kathleen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815771/
https://ncbi.nlm.nih.gov/pubmed/20140085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008938
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