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ModuleDigger: an itemset mining framework for the detection of cis-regulatory modules

BACKGROUND: The detection of cis-regulatory modules (CRMs) that mediate transcriptional responses in eukaryotes remains a key challenge in the postgenomic era. A CRM is characterized by a set of co-occurring transcription factor binding sites (TFBS). In silico methods have been developed to search f...

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Autors principals: Sun, Hong, De Bie, Tijl, Storms, Valerie, Fu, Qiang, Dhollander, Thomas, Lemmens, Karen, Verstuyf, Annemieke, De Moor, Bart, Marchal, Kathleen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648767/
https://ncbi.nlm.nih.gov/pubmed/19208131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-S1-S30
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