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Structure of uracil-DNA N-glycosylase (UNG) from Vibrio cholerae: mapping temperature adaptation through structural and mutational analysis

The crystal structure of Vibrio cholerae uracil-DNA N-glycosylase (vcUNG) has been determined to 1.5 Å resolution. Based on this structure, a homology model of Aliivibrio salmonicida uracil-DNA N-glycosylase (asUNG) was built. A previous study demonstrated that asUNG possesses typical cold-adapted f...

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Autori principali: Raeder, Inger Lin Uttakleiv, Moe, Elin, Willassen, Nils Peder, Smalås, Arne O., Leiros, Ingar
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815677/
https://ncbi.nlm.nih.gov/pubmed/20124707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109052063
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