Comparison of Restriction Fragment Length Polymorphism with the Polymorphic Guanine-Cytosine-Rich Sequence and Spoligotyping for Differentiation of Mycobacterium tuberculosis Isolates with Five or Fewer Copies of IS6110

The use of IS6110 as a marker for molecular epidemiological studies is limited when a Mycobacterium tuberculosis isolate has five or fewer copies of IS6110. Restriction fragment length polymorphism analysis with a highly polymorphic GC-rich repetitive sequence located in the plasmid pTBN12 (PGRS RFL...

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Main Authors: Flores, Laura, Jarlsberg, Leah G., Kim, Elizabeth Y., Osmond, Dennis, Grinsdale, Jennifer, Kawamura, Masae, Desmond, Ed, Hopewell, Philip C., Kato-Maeda, Midori
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Mycobacteriology and Aerobic Actinomycetes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815604/
https://ncbi.nlm.nih.gov/pubmed/20032250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01604-09
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