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A G(1) Checkpoint Mediated by the Retinoblastoma Protein That Is Dispensable in Terminal Differentiation but Essential for Senescence

Terminally differentiated cell types are needed to live and function in a postmitotic state for a lifetime. Cellular senescence is another type of permanent arrest that blocks the proliferation of cells in response to genotoxic stress. Here we show that the retinoblastoma protein (pRB) uses a mechan...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Talluri, Srikanth, Isaac, Christian E., Ahmad, Mohammad, Henley, Shauna A., Francis, Sarah M., Martens, Alison L., Bremner, Rod, Dick, Frederick A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815577/
https://ncbi.nlm.nih.gov/pubmed/20008551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01168-09
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