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The Ubiquitin Ligase Hul5 Promotes Proteasomal Processivity
The 26S proteasome is a large cytoplasmic protease that degrades polyubiquitinated proteins to short peptides in a processive manner. The proteasome 19S regulatory subcomplex tethers the target protein via its polyubiquitin adduct and unfolds the target polypeptide, which is then threaded into the p...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2815575/ https://ncbi.nlm.nih.gov/pubmed/20008553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00909-09 |
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