Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes

INTRODUCTION: Breast cancer subtypes exhibit different genomic aberration patterns with a tendency for high-level amplifications in distinct chromosomal regions. These genomic aberrations may drive carcinogenesis through the upregulation of proto-oncogenes. We have characterized DNA amplification at...

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Main Authors: Melchor, Lorenzo, Saucedo-Cuevas, Laura Paula, Muñoz-Repeto, Iván, Rodríguez-Pinilla, Socorro María, Honrado, Emiliano, Campoverde, Alfredo, Palacios, Jose, Nathanson, Katherine L, García, María José, Benítez, Javier
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815550/
https://ncbi.nlm.nih.gov/pubmed/19995430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2456
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