Recurrent Amplification at 13q34 Targets at CUL4A, IRS2, and TFDP1 As an Independent Adverse Prognosticator in Intrahepatic Cholangiocarcinoma

Amplification of genes at 13q34 has been reported to be associated with tumor proliferation and progression in diverse types of cancers. However, its role in intrahepatic cholangiocarcinoma (iCCA) has yet to be explored. We examined two iCCA cell lines and 86 cases of intrahepatic cholangiocarcinoma...

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Bibliographic Details
Published in:PLoS One
Main Authors: Liu, Ting-Ting, You, Huey-Ling, Weng, Shao-Wen, Wei, Yu-Ching, Eng, Hock-Liew, Huang, Wan-Ting
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686179/
https://ncbi.nlm.nih.gov/pubmed/26684807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145388
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