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A five-amino-acid motif in the undefined region of the TLR8 ectodomain is required for species-specific ligand recognition
Toll-like receptors play important roles in regulating immunity against microbial infections. Toll-like receptor 8 (TLR8) belongs to a subfamily comprising TLR7, TLR8 and TLR9. Human TLR8 mediates anti-viral immunity by recognizing ssRNA viruses, and triggers potent anti-viral and antitumor immune r...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2815190/ https://ncbi.nlm.nih.gov/pubmed/20004021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.11.003 |
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