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Translation factor LepA contributes to tellurite resistance in Escherichia coli but plays no apparent role in the fidelity of protein synthesis

LepA is a translational GTPase highly conserved in bacterial lineages. While it has been shown that LepA can catalyze reverse ribosomal translocation in vitro, the role of LepA in the cell remains unclear. Here, we show that deletion of the lepA gene (ΔlepA) in E. coli causes hypersensitivity to pot...

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Detalhes bibliográficos
Main Authors: Shoji, Shinichiro, Janssen, Brian D., Hayes, Christopher S., Fredrick, Kurt
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815024/
https://ncbi.nlm.nih.gov/pubmed/19925844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2009.11.002
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