The Kynurenine Pathway in Adolescent Depression: Preliminary Findings from a Proton MR Spectroscopy Study

BACKGROUND: Cytokine induction of the enzyme indoleamine 2,3-dioxygenase (IDO) has been implicated in the development of major depressive disorder (MDD). IDO metabolizes tryptophan (TRP) into kynurenine (KYN), thereby decreasing TRP availability to the brain. KYN is further metabolized into several...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Gabbay, Vilma, Liebes, Leonard, Katz, Yisrael, Liu, Songtao, Mendoza, Sandra, Babb, James S., Klein, Rachel G., Gonen, Oded
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815014/
https://ncbi.nlm.nih.gov/pubmed/19778568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2009.09.015
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi