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THE CRITICAL ROLE OF THE CELLULAR THIOL HOMEOSTASIS IN CADMIUM PERTURBATION OF THE LUNG EXTRACELLULAR MATRIX
Cadmium (Cd) inhalation can result in emphysema. Cd exposure of rat lung fibroblasts (RFL6) enhanced levels of metal scavenging thiols, e.g., metallothionein (MT) and glutathione (GSH), and the heavy chain of γ-glutamylcysteine synthetase (γ-GCS), a key enzyme for GSH biosynthesis, concomitant with...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814991/ https://ncbi.nlm.nih.gov/pubmed/19879314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2009.10.021 |
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