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THE CRITICAL ROLE OF THE CELLULAR THIOL HOMEOSTASIS IN CADMIUM PERTURBATION OF THE LUNG EXTRACELLULAR MATRIX

Cadmium (Cd) inhalation can result in emphysema. Cd exposure of rat lung fibroblasts (RFL6) enhanced levels of metal scavenging thiols, e.g., metallothionein (MT) and glutathione (GSH), and the heavy chain of γ-glutamylcysteine synthetase (γ-GCS), a key enzyme for GSH biosynthesis, concomitant with...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhao, Yinzhi, Chen, Lijun, Gao, Song, Toselli, Paul, Stone, Phillip, Li, Wande
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814991/
https://ncbi.nlm.nih.gov/pubmed/19879314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2009.10.021
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