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THE CRITICAL ROLE OF THE CELLULAR THIOL HOMEOSTASIS IN CADMIUM PERTURBATION OF THE LUNG EXTRACELLULAR MATRIX

Cadmium (Cd) inhalation can result in emphysema. Cd exposure of rat lung fibroblasts (RFL6) enhanced levels of metal scavenging thiols, e.g., metallothionein (MT) and glutathione (GSH), and the heavy chain of γ-glutamylcysteine synthetase (γ-GCS), a key enzyme for GSH biosynthesis, concomitant with...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhao, Yinzhi, Chen, Lijun, Gao, Song, Toselli, Paul, Stone, Phillip, Li, Wande
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814991/
https://ncbi.nlm.nih.gov/pubmed/19879314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2009.10.021
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