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Homogeneous nanoparticles to enhance the efficiency of a hydrophobic drug, anti-hyperlipidemic Probucol, characterized by solid-state NMR
A low absorption in the gastrointestinal tract of hydrophobic pharmaceutical compounds in use today considerably limits their bioavailability and therefore they are taken in large doses in order to reach the therapeutic plasma concentration, which inevitably results in undesired side effects. In thi...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814972/ https://ncbi.nlm.nih.gov/pubmed/19938876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900254y |
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