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Transduction efficiency of AAV 2/6, 2/8 and 2/9 vectors for delivering genes in human corneal fibroblasts

In the present study, cellular tropism and relative transduction efficiency of AAV2/6, AAV2/8 and AAV2/9 vectors have been tested for the cornea using primary cultures of human corneal fibroblasts. The AAV6, AAV8 and AAV9 serotypes having AAV2 ITR plasmid encoding for alkaline phosphatase (AP) gene...

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Detalhes bibliográficos
Main Authors: Sharma, Ajay, Ghosh, Arkasubhra, Hansen, Eric T., Newman, Jason M., Mohan, Rajiv R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814910/
https://ncbi.nlm.nih.gov/pubmed/19616080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2009.07.005
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