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The c-Jun N-terminal Kinase 1 (JNK1) in spinal astrocytes is required for the maintenance of bilateral mechanical allodynia under a persistent inflammatory pain condition

Peripheral inflammation induces persistent central sensitization characterized by mechanical allodynia and heat hyperalgesia that are mediated by distinct mechanisms. Compared to well-demonstrated mechanisms of heat hyperalgesia, mechanisms underlying the development of mechanical allodynia and cont...

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Autors principals: Gao, Yong-Jing, Xu, Zhen-Zhong, Liu, Yen-Chin, Wen, Yeong-Ray, Decosterd, Isabelle, Ji, Ru-Rong
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814908/
https://ncbi.nlm.nih.gov/pubmed/20022176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2009.11.017
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