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The self-antigen, thyroglobulin, induces antigen-experienced CD4(+) T cells from healthy donors to proliferate and promote production of the regulatory cytokine, interleukin-10, by monocytes

Thyroglobulin (TG), as autoantigen, induces in vitro proliferation of T and B cells from normal individuals, but the cytokine production differs from that in patients with autoimmune thyroid disease. Here, we investigate whether normal T cells responding to TG are naive, or have previously encounter...

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Detalhes bibliográficos
Main Authors: Nielsen, Claus H, Galdiers, Marcel P, Hedegaard, Chris J, Leslie, R Graham Q
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814470/
https://ncbi.nlm.nih.gov/pubmed/19845795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03183.x
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