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Axonal Transport Rates In Vivo Are Unaffected by Tau Deletion or Overexpression in Mice

Elevated tau expression has been proposed as a possible basis for impaired axonal transport in Alzheimer's disease. To address this hypothesis, we analyzed the movement of pulse radiolabeled proteins in vivo along retinal ganglion cell (RGC) axons of mice that lack tau or overexpress human tau...

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Detalhes bibliográficos
Main Authors: Yuan, Aidong, Kumar, Asok, Peterhoff, Corrinne, Duff, Karen, Nixon, Ralph A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814454/
https://ncbi.nlm.nih.gov/pubmed/18272688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5242-07.2008
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