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Axonal Transport Rates In Vivo Are Unaffected by Tau Deletion or Overexpression in Mice

Elevated tau expression has been proposed as a possible basis for impaired axonal transport in Alzheimer's disease. To address this hypothesis, we analyzed the movement of pulse radiolabeled proteins in vivo along retinal ganglion cell (RGC) axons of mice that lack tau or overexpress human tau...

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Bibliografische gegevens
Hoofdauteurs: Yuan, Aidong, Kumar, Asok, Peterhoff, Corrinne, Duff, Karen, Nixon, Ralph A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814454/
https://ncbi.nlm.nih.gov/pubmed/18272688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5242-07.2008
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