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Immunodominance of CD4 T cells to foreign antigens is peptide intrinsic and independent of molecular context: Implications for vaccine design

Immunodominance refers to the restricted peptide specificity of T cells that are detectable after an adaptive immune response. For CD4 T cells, many of the mechanisms used to explain this selectivity suggest that events related to antigen processing play a major role in determining a peptide’s abili...

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Detalhes bibliográficos
Main Authors: Weaver, Jason M., Lazarski, Christopher A., Richards, Katherine A., Chaves, Francisco A., Jenks, Scott A., Menges, Paula R., Sant, Andrea J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814425/
https://ncbi.nlm.nih.gov/pubmed/18713974
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