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Combined Use of MS2 and PP7 Coat Fusions Shows that TIA-1 Dominates hnRNP A1 for K-SAM Exon Splicing Control

Splicing of the FGFR2 K-SAM exon is repressed by hnRNP A1 bound to the exon and activated by TIA-1 bound to the downstream intron. Both proteins are expressed similarly by cells whether they splice the exon or not, so it is important to know which one is dominant. To answer this question, we used ba...

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Detalhes bibliográficos
Main Authors: Gesnel, Marie-Claude, Del Gatto-Konczak, Fabienne, Breathnach, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814235/
https://ncbi.nlm.nih.gov/pubmed/20130820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/104853
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