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Cytoplasmic Functions of the Tumor Suppressor p53
The principal tumor suppressor protein, p53, accumulates in cells in response to DNA damage, oncogene activation, and other stresses. It acts as a nuclear transcription factor that transactivates genes involved in apoptosis, cell cycle regulation, and numerous other processes. An emerging area of re...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814168/ https://ncbi.nlm.nih.gov/pubmed/19407794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07986 |
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