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The Frizzled Extracellular Domain Is a Ligand for Van Gogh/Stbm during Nonautonomous Planar Cell Polarity Signaling
The Frizzled (Fz) receptor is required cell autonomously in Wnt/β-catenin and planar cell polarity (PCP) signaling. In addition to these requirements, Fz acts nonautonomously during PCP establishment: wild-type cells surrounding fz(−) patches reorient toward the fz(−) cells. The molecular mechanism(...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814157/ https://ncbi.nlm.nih.gov/pubmed/18804440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.08.004 |
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