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Frizzled-induced Van Gogh phosphorylation by CK1ε promotes asymmetric localization of core PCP factors in Drosophila

Epithelial tissues are polarized along two axes. In addition to apical-basal polarity they are often polarized within the plane of the epithelium, so-called Planar Cell Polarity (PCP). PCP depends upon Wnt/Frizzled (Fz) signaling factors, including Fz itself and Van Gogh (Vang/Vangl). We sought to u...

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Publicado en:Cell Rep
Autores principales: Kelly, Lindsay K., Wu, Jun, Yanfeng, Wang A., Mlodzik, Marek
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945453/
https://ncbi.nlm.nih.gov/pubmed/27346358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.010
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