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ESTROGEN SUPPRESSES CARDIAC IL-6 AFTER TRAUMA-HEMORRHAGE VIA A HYPOXIA-INDUCIBLE FACTOR 1α–MEDIATED PATHWAY

Cardiac dysfunction is a major concern after trauma-hemorrhage, and increased IL-6 is one of the underlying causes for producing the dysfunction. Studies have shown that administration of 17β-estradiol (estrogen) after trauma-hemorrhage normalized cardiac IL-6 levels and restored cardiac functions u...

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Detalhes bibliográficos
Main Authors: Nickel, Eike A., Hsieh, Chi-Hsun, Chen, Jianguo G., Schwacha, Martin G., Chaudry, Irshad H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814124/
https://ncbi.nlm.nih.gov/pubmed/18791496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181862fdd
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