Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo

Attaching and effacing (A/E) lesions and actin polymerization, the hallmark of enteropathogenic Escherichia coli (EPEC), enterohemorrhagic E. coli (EHEC) and Citrobacter rodentium (CR) infections, are dependent on the effector Tir. Phosphorylation of Tir(EPEC/CR) Y474/1 leads to recruitment of Nck a...

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Main Authors: Crepin, Valérie F, Girard, Francis, Schüller, Stephanie, Phillips, Alan D, Mousnier, Aurelie, Frankel, Gad
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2010
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814079/
https://ncbi.nlm.nih.gov/pubmed/19889090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06938.x
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