Structural Basis for Complex Formation between Human IRSp53 and the Translocated Intimin Receptor Tir of Enterohemorrhagic E. coli

Actin assembly beneath enterohemorrhagic E. coli (EHEC) attached to its host cell is triggered by the intracellular interaction of its translocated effector proteins Tir and EspF(U) with human IRSp53 family proteins and N-WASP. Here, we report the structure of the N-terminal I-BAR domain of IRSp53 i...

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Hauptverfasser: de Groot, Jens C., Schlüter, Kai, Carius, Yvonne, Quedenau, Claudia, Vingadassalom, Didier, Faix, Jan, Weiss, Stefanie M., Reichelt, Joachim, Standfuß-Gabisch, Christine, Lesser, Cammie F., Leong, John M., Heinz, Dirk W., Büssow, Konrad, Stradal, Theresia E.B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063679/
https://ncbi.nlm.nih.gov/pubmed/21893288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.06.015
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