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Multicomponent Reaction Discovery: Three-Component Synthesis of Spirooxindoles

[Image: see text] The Lewis acid catalyzed, three-component reaction of isatin and two 1,3-dicarbonyl compounds is reported. Reactions proceed with high efficiency under mild reaction conditions and with good functional group tolerance to afford spirooxindole pyranochromenedione derivatives.

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Main Authors: Liang, Bo, Kalidindi, Srinivas, Porco, John A., Stephenson, Corey R. J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814073/
https://ncbi.nlm.nih.gov/pubmed/20050598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol902764k
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