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Metabolic characterization of a mouse deficient in all known leptin receptor isoforms

We have characterized a newly generated mouse model of obesity, a mouse strain deficient in all five previously described leptin receptor isoforms. These transgenic mice, named the db(333)/db(333) mice, were identified from an ENU mutagenesis screen and carry a point mutation in the seventh exon of...

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Hlavní autoři: Osborn, Olivia, Sanchez-Alavez, Manuel, Brownell, Sara E., Ross, Brendon, Klaus, Joe, Dubins, Jeffrey, Beutler, Bruce, Conti, Bruno, Bartfai, Tamas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813927/
https://ncbi.nlm.nih.gov/pubmed/19582570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-009-9427-x
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